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Melanoma and the Unfolded Protein Response

The UPR (unfolded protein response) has been identified as a key factor in the progression and metastasis of cancers, notably melanoma. Several mediators of the UPR are upregulated in cancers, e.g., high levels of GRP78 (glucose-regulator protein 78 kDa) correlate with progression and poor outcome i...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Sykes, Erin K., Mactier, Swetlana, Christopherson, Richard I.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810114/
https://ncbi.nlm.nih.gov/pubmed/26927180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers8030030
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