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The single transmembrane segment determines the modulatory function of the BK channel auxiliary γ subunit

The large-conductance, calcium-activated potassium (BK) channels consist of the pore-forming, voltage- and Ca(2+)-sensing α subunits (BKα) and the tissue-specific auxiliary β and γ subunits. The BK channel γ1 subunit is a leucine-rich repeat (LRR)–containing membrane protein that potently facilitate...

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Bibliographic Details
Published in:J Gen Physiol
Main Authors: Li, Qin, Guan, Xin, Yen, Karen, Zhang, Jiyuan, Yan, Jiusheng
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810070/
https://ncbi.nlm.nih.gov/pubmed/27022192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511551
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