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Relationship between auxiliary gamma subunits and mallotoxin on BK channel modulation

The large-conductance, calcium- and voltage-activated K(+)(BK) channel consists of the pore-forming α subunits (BKα) and auxiliary subunits. The auxiliary γ1-3 subunits potently modulate the BK channel by shifting its voltage-dependence of channel activation toward the hyperpolarizing direction by a...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Guan, Xin, Li, Qin, Yan, Jiusheng
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292707/
https://ncbi.nlm.nih.gov/pubmed/28165042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42240
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