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Regulation of skeletal growth and mineral acquisition by the GH/IGF-1 axis: Lessons from mouse models

The growth hormone (GH) and its downstream mediator, the insulin-like growth factor-1 (IGF-1), construct a pleotropic axis affecting growth, metabolism, and organ function. Serum levels of GH/IGF-1 rise during pubertal growth and associate with peak bone acquisition, while during aging their levels...

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Dettagli Bibliografici
Pubblicato in:Growth Horm IGF Res
Autori principali: Yakar, Shoshana, Isaksson, Olle
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809789/
https://ncbi.nlm.nih.gov/pubmed/26432542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2015.09.004
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