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Does the GH/IGF-1 axis contribute to skeletal sexual dimorphism? Evidence from mouse studies

The contribution of the gonadotropic axis to skeletal sexual dimorphism (SSD) was clarified in recent years. Studies with animal models of estrogen receptor (ER) or androgen receptor (AR) null mice, as well as mice with bone cell-specific ablation of ER or AR, revealed that both hormones play major...

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Pubblicato in:Growth Horm IGF Res
Autori principali: Liu, Zhongbo, Mohan, Subburaman, Yakar, Shoshana
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488285/
https://ncbi.nlm.nih.gov/pubmed/26843472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2015.12.004
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