Blocking LFA-1 Activation with Lovastatin Prevents Graft-versus-Host Disease in Mouse Bone Marrow Transplantation

Graft-versus-host disease (GVHD) following bone marrow transplantation (BMT) is mediated by alloreactive donor T lymphocytes. Migration and activation of donor-derived T lymphocytes play critical roles in the development of GVHD. Leukocyte function associated antigen-1 (LFA-1) regulates T cell adhes...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Biol Blood Marrow Transplant
Huvudupphovsmän: Wang, Yang, Li, Dan, Jones, Dan, Bassett, Roland, Sale, George E., Khalili, Jahan, Komanduri, Krishna V., Couriel, Daniel R., Champlin, Richard E., Molldrem, Jeffrey J., Ma, Qing
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809421/
https://ncbi.nlm.nih.gov/pubmed/19896074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2009.08.013
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk