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Hypoxia-Inducible Factor 1 Mediates Upregulation of Telomerase (hTERT)

Hypoxia occurs during the development of the placenta in the first trimester and correlates with both trophoblast differentiation and the induction of telomerase activity through hTERT expression. We sought to determine the mechanism of regulation of hTERT expression during hypoxia. We show that hyp...

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Autori principali: Nishi, Hirotaka, Nakada, Toshihide, Kyo, Satoru, Inoue, Masaki, Shay, Jerry W., Isaka, Keiichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC480902/
https://ncbi.nlm.nih.gov/pubmed/15199161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.6076-6083.2004
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