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Hypoxia-Inducible Factor 1 Mediates Upregulation of Telomerase (hTERT)

Hypoxia occurs during the development of the placenta in the first trimester and correlates with both trophoblast differentiation and the induction of telomerase activity through hTERT expression. We sought to determine the mechanism of regulation of hTERT expression during hypoxia. We show that hyp...

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Autors principals: Nishi, Hirotaka, Nakada, Toshihide, Kyo, Satoru, Inoue, Masaki, Shay, Jerry W., Isaka, Keiichi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC480902/
https://ncbi.nlm.nih.gov/pubmed/15199161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.6076-6083.2004
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