Caricamento...

Role for Cdk1 (Cdc2)/Cyclin A in Preventing the Mammalian Origin Recognition Complex's Largest Subunit (Orc1) from Binding to Chromatin during Mitosis

The eukaryotic origin recognition complex (ORC) selects the genomic sites where prereplication complexes are assembled and DNA replication begins. In proliferating mammalian cells, ORC activity appears to be regulated by reducing the affinity of the Orc1 subunit for chromatin during S phase and then...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Li, Cong-jun, Vassilev, Alex, DePamphilis, Melvin L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC480893/
https://ncbi.nlm.nih.gov/pubmed/15199143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.5875-5886.2004
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !