טוען...
Role for Cdk1 (Cdc2)/Cyclin A in Preventing the Mammalian Origin Recognition Complex's Largest Subunit (Orc1) from Binding to Chromatin during Mitosis
The eukaryotic origin recognition complex (ORC) selects the genomic sites where prereplication complexes are assembled and DNA replication begins. In proliferating mammalian cells, ORC activity appears to be regulated by reducing the affinity of the Orc1 subunit for chromatin during S phase and then...
שמור ב:
Main Authors: | , , |
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פורמט: | Artigo |
שפה: | Inglês |
יצא לאור: |
American Society for Microbiology
2004
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נושאים: | |
גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC480893/ https://ncbi.nlm.nih.gov/pubmed/15199143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.5875-5886.2004 |
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