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Structural elements that govern Sec14-like PITP sensitivities to potent small molecule inhibitors

Sec14-like phosphatidylinositol transfer proteins (PITPs) play important biological functions in integrating multiple aspects of intracellular lipid metabolism with phosphatidylinositol-4-phosphate signaling. As such, these proteins offer new opportunities for highly selective chemical interference...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Khan, Danish, McGrath, Kaitlyn R., Dorosheva, Oleksandra, Bankaitis, Vytas A., Tripathi, Ashutosh
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808773/
https://ncbi.nlm.nih.gov/pubmed/26921357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M066381
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