Functional diversification of the chemical landscapes of yeast Sec14-like phosphatidylinositol transfer protein lipid-binding cavities

Phosphatidylinositol-transfer proteins (PITPs) are key regulators of lipid signaling in eukaryotic cells. These proteins both potentiate the activities of phosphatidylinositol (PtdIns) 4-OH kinases and help channel production of specific pools of phosphatidylinositol 4-phosphate (PtdIns(4)P) dedicat...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Tripathi, Ashutosh, Martinez, Elliott, Obaidullah, Ahmad J., Lete, Marta G., Lönnfors, Max, Khan, Danish, Soni, Krishnakant G., Mousley, Carl J., Kellogg, Glen E., Bankaitis, Vytas A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
Soggetti:
Lipids
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6916498/
https://ncbi.nlm.nih.gov/pubmed/31690622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011153
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