Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR:LA-cp rat

Vaccenic acid (VA), the predominant ruminant-derived trans fat in the food chain, ameliorates hyperlipidemia, yet mechanisms remain elusive. We investigated whether VA could influence tissue endocannabinoids (ECs) by altering the availability of their biosynthetic precursor, arachidonic acid (AA), i...

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Bibliografski detalji
Izdano u:J Lipid Res
Glavni autori: Jacome-Sosa, Miriam, Vacca, Claudia, Mangat, Rabban, Diane, Abdoulaye, Nelson, Randy C., Reaney, Martin J., Shen, Jianheng, Curtis, Jonathan M., Vine, Donna F., Field, Catherine J., Igarashi, Miki, Piomelli, Daniele, Banni, Sebastiano, Proctor, Spencer D.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2016
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808772/
https://ncbi.nlm.nih.gov/pubmed/26891736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M066308
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