Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR:LA-cp rat

Vaccenic acid (VA), the predominant ruminant-derived trans fat in the food chain, ameliorates hyperlipidemia, yet mechanisms remain elusive. We investigated whether VA could influence tissue endocannabinoids (ECs) by altering the availability of their biosynthetic precursor, arachidonic acid (AA), i...

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Dettagli Bibliografici
Pubblicato in:J Lipid Res
Autori principali: Jacome-Sosa, Miriam, Vacca, Claudia, Mangat, Rabban, Diane, Abdoulaye, Nelson, Randy C., Reaney, Martin J., Shen, Jianheng, Curtis, Jonathan M., Vine, Donna F., Field, Catherine J., Igarashi, Miki, Piomelli, Daniele, Banni, Sebastiano, Proctor, Spencer D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2016
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808772/
https://ncbi.nlm.nih.gov/pubmed/26891736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M066308
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