Vaccenic acid suppresses intestinal inflammation by increasing anandamide and related N-acylethanolamines in the JCR:LA-cp rat

Vaccenic acid (VA), the predominant ruminant-derived trans fat in the food chain, ameliorates hyperlipidemia, yet mechanisms remain elusive. We investigated whether VA could influence tissue endocannabinoids (ECs) by altering the availability of their biosynthetic precursor, arachidonic acid (AA), i...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Jacome-Sosa, Miriam, Vacca, Claudia, Mangat, Rabban, Diane, Abdoulaye, Nelson, Randy C., Reaney, Martin J., Shen, Jianheng, Curtis, Jonathan M., Vine, Donna F., Field, Catherine J., Igarashi, Miki, Piomelli, Daniele, Banni, Sebastiano, Proctor, Spencer D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808772/
https://ncbi.nlm.nih.gov/pubmed/26891736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M066308
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