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Harnessing the Prokaryotic Adaptive Immune System as a Eukaryotic Antiviral Defense
Clustered, regularly interspaced, short palindromic repeats - CRISPR associated (CRISPR-Cas) systems are sequence specific RNA-directed endonuclease complexes that bind and cleave nucleic acids. These systems evolved within prokaryotes as adaptive immune defenses to target and degrade nucleic acids...
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| Veröffentlicht in: | Trends Microbiol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4808413/ https://ncbi.nlm.nih.gov/pubmed/26852268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2016.01.005 |
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