Population Pharmacokinetic Assessment and Pharmacodynamic Implications of Pediatric Cefepime Dosing for Susceptible-Dose-Dependent Organisms

The Clinical and Laboratory Standards Institute (CLSI) revised cefepime (CFP) breakpoints for Enterobacteriaceae in 2014, and MICs of 4 and 8 μg/ml were reclassified as susceptible-dose dependent (SDD). Pediatric dosing to provide therapeutic concentrations against SDD organisms has not been defined...

Full description

Saved in:
Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Shoji, Kensuke, Bradley, John S., Reed, Michael D., van den Anker, John N., Domonoske, Christine, Capparelli, Edmund V.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808231/
https://ncbi.nlm.nih.gov/pubmed/26810655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02592-15
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items