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Luciferase-Based, High-Throughput Assay for Screening and Profiling Transmission-Blocking Compounds against Plasmodium falciparum Gametocytes

The discovery of new antimalarial drugs able to target both the asexual and gametocyte stages of Plasmodium falciparum is critical to the success of the malaria eradication campaign. We have developed and validated a robust, rapid, and cost-effective high-throughput reporter gene assay to identify c...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Lucantoni, Leonardo, Fidock, David A., Avery, Vicky M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808229/
https://ncbi.nlm.nih.gov/pubmed/26787698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01949-15
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