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A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds

Plasmodium falciparum gametocytes, specifically the mature stages, are the only malaria parasite stage in humans transmissible to the mosquito vector. Anti-malarial drugs capable of killing these forms are considered essential for the eradication of malaria and tools allowing the screening of large...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lucantoni, Leonardo, Silvestrini, Francesco, Signore, Michele, Siciliano, Giulia, Eldering, Maarten, Dechering, Koen J., Avery, Vicky M., Alano, Pietro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639769/
https://ncbi.nlm.nih.gov/pubmed/26553647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16414
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