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A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds

Plasmodium falciparum gametocytes, specifically the mature stages, are the only malaria parasite stage in humans transmissible to the mosquito vector. Anti-malarial drugs capable of killing these forms are considered essential for the eradication of malaria and tools allowing the screening of large...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Lucantoni, Leonardo, Silvestrini, Francesco, Signore, Michele, Siciliano, Giulia, Eldering, Maarten, Dechering, Koen J., Avery, Vicky M., Alano, Pietro
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639769/
https://ncbi.nlm.nih.gov/pubmed/26553647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16414
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