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A simple and predictive phenotypic High Content Imaging assay for Plasmodium falciparum mature gametocytes to identify malaria transmission blocking compounds

Plasmodium falciparum gametocytes, specifically the mature stages, are the only malaria parasite stage in humans transmissible to the mosquito vector. Anti-malarial drugs capable of killing these forms are considered essential for the eradication of malaria and tools allowing the screening of large...

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Lucantoni, Leonardo, Silvestrini, Francesco, Signore, Michele, Siciliano, Giulia, Eldering, Maarten, Dechering, Koen J., Avery, Vicky M., Alano, Pietro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4639769/
https://ncbi.nlm.nih.gov/pubmed/26553647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16414
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