Crystal structure of murine cyclophilin C complexed with immunosuppressive drug cyclosporin A.
Cyclophilin is a cellular receptor for the immunosuppressive drug cyclosporin A (CsA). Cyclophilin C (CyPC) is highly expressed in murine kidney, making it a potential mediator of the nephrotoxic effects of CsA. The structure of murine CyPC complexed with CsA has been solved and refined to an R fact...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48082/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.24.11850 |
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