Crystal structure of murine cyclophilin C complexed with immunosuppressive drug cyclosporin A.

Cyclophilin is a cellular receptor for the immunosuppressive drug cyclosporin A (CsA). Cyclophilin C (CyPC) is highly expressed in murine kidney, making it a potential mediator of the nephrotoxic effects of CsA. The structure of murine CyPC complexed with CsA has been solved and refined to an R fact...

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Hlavní autoři: Ke, H, Zhao, Y, Luo, F, Weissman, I, Friedman, J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC48082/
https://ncbi.nlm.nih.gov/pubmed/8265636
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