Contribution of Population Pharmacokinetics to Dose Optimization of Ganciclovir-Valganciclovir in Solid-Organ Transplant Patients

Treatment of solid-organ transplant (SOT) patients with ganciclovir (GCV)-valganciclovir (VGCV) according to the manufacturer's recommendations may result in over- or underexposure. Bayesian prediction based on a population pharmacokinetics model may optimize GCV-VGCV dosing, achieving the area...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Padullés, A., Colom, H., Bestard, O., Melilli, E., Sabé, N., Rigo, R., Niubó, J., Torras, J., Lladó, L., Manito, N., Caldés, A., Cruzado, J. M., Grinyó, J. M., Lloberas, N.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808182/
https://ncbi.nlm.nih.gov/pubmed/26824942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02130-15
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