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Amino Acid Substitutions Account for Most MexS Alterations in Clinical nfxC Mutants of Pseudomonas aeruginosa
Multidrug-resistant mutants of Pseudomonas aeruginosa that overproduce the active efflux system MexEF-OprN (called nfxC mutants) have rarely been characterized in the hospital setting. Screening of 221 clinical strains exhibiting a reduced susceptibility to ciprofloxacin (a substrate of MexEF-OprN)...
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| Publicado no: | Antimicrob Agents Chemother |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4808181/ https://ncbi.nlm.nih.gov/pubmed/26833155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02622-15 |
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