HBx sensitizes hepatocellular carcinoma cells to lapatinib by up-regulating ErbB3

Poor prognosis of hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) involves HBV X protein (HBx)-induced tumor progression. HBx also contributes to chemo-resistance via inducing the expressions of anti-apoptosis and multiple drug resistance genes. However, the impact of HBx expressio...

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Vydáno v:Oncotarget
Hlavní autoři: Chen, Jhen-Yu, Chen, Yun-Ju, Yen, Chia-Jui, Chen, Wen-Shu, Huang, Wei-Chien
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808012/
https://ncbi.nlm.nih.gov/pubmed/26595522
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