Nuclear IKKα mediates microRNA-7/-103/107/21 inductions to downregulate maspin expression in response to HBx overexpression

Maspin is a tumor suppressor that stimulates apoptosis and inhibits metastasis in various cancer types, including hepatocellular carcinoma (HCC). Our previous study has demonstrated that HBx induced microRNA-7, 103, 107, and 21 expressions to suppress maspin expression, leading to metastasis, chemor...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Chen, Wen-Shu, Liu, Liang-Chih, Yen, Chia-Jui, Chen, Yun-Ju, Chen, Jhen-Yu, Ho, Chien-Yi, Liu, Shu-Hui, Chen, Ching-Chow, Huang, Wei-Chien
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302916/
https://ncbi.nlm.nih.gov/pubmed/27409165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10462
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