An hTERT/ZEB1 complex directly regulates E-cadherin to promote epithelial-to-mesenchymal transition (EMT) in colorectal cancer

In human cancer, high telomerase expression is correlated with tumor aggressiveness and metastatic potential. Telomerase activation occurs through telomerase reverse transcriptase (hTERT) induction, which contributes to malignant transformation by stabilizing telomeres. Previous studies have shown t...

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Vydáno v:Oncotarget
Hlavní autoři: Qin, Yong, Tang, Bo, Hu, Chang-Jiang, Xiao, Yu-Feng, Xie, Rui, Yong, Xin, Wu, Yu-Yun, Dong, Hui, Yang, Shi-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808003/
https://ncbi.nlm.nih.gov/pubmed/26540342
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