An hTERT/ZEB1 complex directly regulates E-cadherin to promote epithelial-to-mesenchymal transition (EMT) in colorectal cancer

In human cancer, high telomerase expression is correlated with tumor aggressiveness and metastatic potential. Telomerase activation occurs through telomerase reverse transcriptase (hTERT) induction, which contributes to malignant transformation by stabilizing telomeres. Previous studies have shown t...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Qin, Yong, Tang, Bo, Hu, Chang-Jiang, Xiao, Yu-Feng, Xie, Rui, Yong, Xin, Wu, Yu-Yun, Dong, Hui, Yang, Shi-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4808003/
https://ncbi.nlm.nih.gov/pubmed/26540342
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