Enhanced dissolution and oral absorption of tacrolimus by supersaturable self-emulsifying drug delivery system

A new Soluplus (polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol graft copolymer)-based supersaturable self-emulsifying drug delivery system (S-SEDDS) was formulated to enhance oral absorption of tacrolimus (FK506) with minimal use of oil, surfactant, and cosurfactant. A high payload supe...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Lee, Dae Ro, Ho, Myoung Jin, Jung, Hyuck Jun, Cho, Ha Ra, Park, Jun Seo, Yoon, Suk-Hyun, Choi, Yong Seok, Choi, Young Wook, Oh, Chung-Hun, Kang, Myung Joo
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807944/
https://ncbi.nlm.nih.gov/pubmed/27051286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S102991
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