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Direct Acylation of C(sp(3))–H Bonds Enabled by Nickel and Photoredox Catalysis
Using nickel and photoredox catalysis, the direct functionalization of C(sp(3))–H bonds of N-aryl amines by acyl electrophiles is described. The method affords a diverse range of α-amino ketones at room temperature and is amenable to late-stage coupling of complex and biologically relevant groups. C...
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| I publikationen: | Angew Chem Int Ed Engl |
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| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4807873/ https://ncbi.nlm.nih.gov/pubmed/26890705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201511438 |
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