Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies(1)

Mendelian randomization (MR) is an increasingly important tool for appraising causality in observational epidemiology. The technique exploits the principle that genotypes are not generally susceptible to reverse causation bias and confounding, reflecting their fixed nature and Mendel’s first and sec...

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Bibliografski detalji
Izdano u:Am J Clin Nutr
Glavni autori: Haycock, Philip C, Burgess, Stephen, Wade, Kaitlin H, Bowden, Jack, Relton, Caroline, Davey Smith, George
Format: Artigo
Jezik:Inglês
Izdano: American Society for Nutrition 2016
Teme:
Statistical Commentary
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807699/
https://ncbi.nlm.nih.gov/pubmed/26961927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.115.118216
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