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Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies(1)

Mendelian randomization (MR) is an increasingly important tool for appraising causality in observational epidemiology. The technique exploits the principle that genotypes are not generally susceptible to reverse causation bias and confounding, reflecting their fixed nature and Mendel’s first and sec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Am J Clin Nutr
Hauptverfasser: Haycock, Philip C, Burgess, Stephen, Wade, Kaitlin H, Bowden, Jack, Relton, Caroline, Davey Smith, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Nutrition 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807699/
https://ncbi.nlm.nih.gov/pubmed/26961927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/ajcn.115.118216
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