Poly-arginine conjugated triarylmethyl radical as intracellular spin label

Stable triarylmethyl radicals are ideal spin labels used for biomedical electron paramagnetic resonance applications. Previously reported structures exhibit polar charged functions for water solubilization preventing them from crossing the cell membrane. We report the synthesis of a triarylmethyl ra...

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Gepubliceerd in:Bioorg Med Chem Lett
Hoofdauteurs: Driesschaert, Benoit, Bobko, Andrey A., Eubank, Timothy D., Samouilov, Alexandre, Khramtsov, Valery V., Zweier, Jay L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807691/
https://ncbi.nlm.nih.gov/pubmed/26923698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.02.048
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