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Poly-arginine conjugated triarylmethyl radical as intracellular spin label

Stable triarylmethyl radicals are ideal spin labels used for biomedical electron paramagnetic resonance applications. Previously reported structures exhibit polar charged functions for water solubilization preventing them from crossing the cell membrane. We report the synthesis of a triarylmethyl ra...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Driesschaert, Benoit, Bobko, Andrey A., Eubank, Timothy D., Samouilov, Alexandre, Khramtsov, Valery V., Zweier, Jay L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807691/
https://ncbi.nlm.nih.gov/pubmed/26923698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.02.048
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