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Drug Repurposing Identifies Inhibitors of Oseltamivir-Resistant Influenza Viruses
The inhibitor of neuraminidase (NA), oseltamivir, is a widely used anti-influenza drug. However, oseltamivir-resistant H1N1 influenza viruses carrying the H275Y NA mutation spontaneously emerged as a result of natural genetic drift and drug treatment. Because this and other potential mutations may g...
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| Publicado en: | Angew Chem Int Ed Engl |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4807618/ https://ncbi.nlm.nih.gov/pubmed/26833677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201511361 |
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