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Targeted p53 activation by saRNA suppresses human bladder cancer cells growth and metastasis
BACKGROUND: Previous study showed that dsP53-285 has the capacity to induce tumor suppressor gene p53 expression by targeting promoter in non-human primates’ cells. And it is well known that TP53 gene is frequently mutant or inactivated in human bladder cancer. Hereby, whether this small RNA can act...
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| 發表在: | J Exp Clin Cancer Res |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4807596/ https://ncbi.nlm.nih.gov/pubmed/27012825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0329-8 |
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