Splicing-dependent expression of microRNAs of mirtron origin in human digestive and excretory system cancer cells

BACKGROUND: An abundant class of intronic microRNAs (miRNAs) undergoes atypical Drosha-independent biogenesis in which the spliceosome governs the excision of hairpin miRNA precursors, called mirtrons. Although nearly 500 splicing-dependent miRNA candidates have been recently predicted via bioinform...

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Detalles Bibliográficos
Publicado en:Clin Epigenetics
Main Authors: Butkytė, Stasė, Čiupas, Laurynas, Jakubauskienė, Eglė, Vilys, Laurynas, Mocevicius, Paulius, Kanopka, Arvydas, Vilkaitis, Giedrius
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807562/
https://ncbi.nlm.nih.gov/pubmed/27019673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0200-y
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