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Increased Serine-Arginine (SR) Protein Phosphorylation Changes Pre-mRNA Splicing in Hypoxia

The removal of introns from mRNA precursors (pre-mRNAs) is an essential step in eukaryotic gene expression. The splicing machinery heavily contributes to biological complexity and especially to the ability of cells to adapt to altered cellular conditions. Inhibitory PAS domain protein (IPAS), a domi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jakubauskiene, Egle, Vilys, Laurynas, Makino, Yuichi, Poellinger, Lorenz, Kanopka, Arvydas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505053/
https://ncbi.nlm.nih.gov/pubmed/26023237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.639690
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