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Comparison of RELMα and RELMβ Single- and Double-Gene-Deficient Mice Reveals that RELMα Expression Dictates Inflammation and Worm Expulsion in Hookworm Infection

Resistin-like molecules (RELMs) are highly expressed following helminth infection, where they impact both the host and helminth. While RELMα (Retnla) impairs helminth expulsion by inhibiting protective Th2 immunity, RELMβ (Retnlb) can promote its expulsion. We employed Retnla(−/−) and Retnlb(−/−) mi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Infect Immun
Egile Nagusiak: Chen, Gang, Wang, Spencer H., Jang, Jessica C., Odegaard, Justin I., Nair, Meera G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807501/
https://ncbi.nlm.nih.gov/pubmed/26831469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01479-15
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