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Comparison of RELMα and RELMβ Single- and Double-Gene-Deficient Mice Reveals that RELMα Expression Dictates Inflammation and Worm Expulsion in Hookworm Infection
Resistin-like molecules (RELMs) are highly expressed following helminth infection, where they impact both the host and helminth. While RELMα (Retnla) impairs helminth expulsion by inhibiting protective Th2 immunity, RELMβ (Retnlb) can promote its expulsion. We employed Retnla(−/−) and Retnlb(−/−) mi...
Gorde:
Argitaratua izan da: | Infect Immun |
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Egile Nagusiak: | , , , , |
Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
American Society for Microbiology
2016
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4807501/ https://ncbi.nlm.nih.gov/pubmed/26831469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01479-15 |
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