Uncovering an Important Role for YopJ in the Inhibition of Caspase-1 in Activated Macrophages and Promoting Yersinia pseudotuberculosis Virulence

Pathogenic Yersinia species utilize a type III secretion system to translocate Yop effectors into infected host cells. Yop effectors inhibit innate immune responses in infected macrophages to promote Yersinia pathogenesis. In turn, Yersinia-infected macrophages respond to translocation of Yops by ac...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Schoberle, Taylor J., Chung, Lawton K., McPhee, Joseph B., Bogin, Ben, Bliska, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807483/
https://ncbi.nlm.nih.gov/pubmed/26810037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00843-15
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