High-content screening identifies a role for Na(+) channels in insulin production

Insulin production is the central feature of functionally mature and differentiated pancreatic β-cells. Reduced insulin transcription and dedifferentiation have been implicated in type 2 diabetes, making drugs that could reverse these processes potentially useful. We have previously established rati...

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Detalhes bibliográficos
Publicado no:R Soc Open Sci
Main Authors: Szabat, Marta, Modi, Honey, Ramracheya, Reshma, Girbinger, Vroni, Chan, Forson, Lee, Jason T. C., Piske, Micah, Kamal, Sepehr, Carol Yang, Yu Hsuan, Welling, Andrea, Rorsman, Patrik, Johnson, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society Publishing 2015
Assuntos:
Cellular and Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807443/
https://ncbi.nlm.nih.gov/pubmed/27019722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.150306
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