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3,6′-Dithiothalidomide Improves Experimental Stroke Outcome by Suppressing Neuroinflammation

Tumor necrosis factor-α (TNF) plays a prominent role in the brain damage and functional deficits that result from ischemic stroke. It was recently reported that the thalidomide analog 3,6′-dithiothalidomide (3,6′-DT) can selectively inhibit the synthesis of TNF in cultured cells. We therefore tested...

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Detalhes bibliográficos
Publicado no:J Neurosci Res
Main Authors: Yoon, Jeong Seon, Lee, Jong-Hwan, Tweedie, David, Mughal, Mohamed R., Chigurupati, Srinivasulu, Greig, Nigel H., Mattson, Mark P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807430/
https://ncbi.nlm.nih.gov/pubmed/23404341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23190
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