Tumor necrosis factor-α synthesis inhibitor 3,6′-dithiothalidomide attenuates markers of inflammation, Alzheimer pathology and behavioral deficits in animal models of neuroinflammation and Alzheimer’s disease

BACKGROUND: Neuroinflammation is associated with virtually all major neurodegenerative disorders, including Alzheimer’s disease (AD). Although it remains unclear whether neuroinflammation is the driving force behind these disorders, compelling evidence implicates its role in exacerbating disease pro...

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Detalhes bibliográficos
Main Authors: Tweedie, David, Ferguson, Ryan A, Fishman, Kelly, Frankola, Kathryn A, Van Praag, Henriette, Holloway, Harold W, Luo, Weiming, Li, Yazhou, Caracciolo, Luca, Russo, Isabella, Barlati, Sergio, Ray, Balmiki, Lahiri, Debomoy K, Greig, Nigel H, Rosi, Susanna
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405480/
https://ncbi.nlm.nih.gov/pubmed/22642825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-106
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