Arf-like Protein 3 (ARL3) Regulates Protein Trafficking and Ciliogenesis in Mouse Photoreceptors

Arf-like protein 3 (ARL3) is a ubiquitous small GTPase expressed in ciliated cells of plants and animals. Germline deletion of Arl3 in mice causes multiorgan ciliopathy reminiscent of Bardet-Biedl or Joubert syndromes. As photoreceptors are elegantly compartmentalized and have cilia, we probed the f...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Hanke-Gogokhia, Christin, Wu, Zhijian, Gerstner, Cecilia D., Frederick, Jeanne M., Zhang, Houbin, Baehr, Wolfgang
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2016
Subjects:
Neurobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807295/
https://ncbi.nlm.nih.gov/pubmed/26814127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.710954
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items