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Glutathionylation of the Bacterial Hsp70 Chaperone DnaK Provides a Link between Oxidative Stress and the Heat Shock Response

DnaK is the major bacterial Hsp70, participating in DNA replication, protein folding, and the stress response. DnaK cooperates with the Hsp40 co-chaperone DnaJ and the nucleotide exchange factor GrpE. Under non-stress conditions, DnaK binds to the heat shock transcription factor σ(32) and facilitate...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главный автор: Perrett, Sarah
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807281/
https://ncbi.nlm.nih.gov/pubmed/26823468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.673608
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