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A Functional DnaK Dimer Is Essential for the Efficient Interaction with Hsp40 Heat Shock Protein

Highly conserved molecular chaperone Hsp70 heat shock proteins play a key role in maintaining protein homeostasis (proteostasis). DnaK, a major Hsp70 in Escherichia coli, has been widely used as a paradigm for studying Hsp70s. In the absence of ATP, purified DnaK forms low-ordered oligomer, whereas...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sarbeng, Evans Boateng, Liu, Qingdai, Tian, Xueli, Yang, Jiao, Li, Hongtao, Wong, Jennifer Li, Zhou, Lei, Liu, Qinglian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423677/
https://ncbi.nlm.nih.gov/pubmed/25635056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.596288
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