Fluorescence Activated Cell Sorting of Rickettsia prowazekii-Infected Host Cells Based on Bacterial Burden and Early Detection of Fluorescent Rickettsial Transformants

Rickettsia prowazekii, the causative agent of epidemic typhus, is an obligate intracellular bacterium that replicates only within the cytosol of a eukaryotic host cell. Despite the barriers to genetic manipulation that such a life style creates, rickettsial mutants have been generated by transposon...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Driskell, Lonnie O., Tucker, Aimee M., Woodard, Andrew, Wood, Raphael R., Wood, David O.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807063/
https://ncbi.nlm.nih.gov/pubmed/27010457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152365
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