Spontaneous Physical Activity Downregulates Pax7 in Cancer Cachexia

Emerging evidence suggests that the muscle microenvironment plays a prominent role in cancer cachexia. We recently showed that NF-kB-induced Pax7 overexpression impairs the myogenic potential of muscle precursors in cachectic mice, suggesting that lowering Pax7 expression may be beneficial in cancer...

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Veröffentlicht in:Stem Cells Int
Hauptverfasser: Coletti, Dario, Aulino, Paola, Pigna, Eva, Barteri, Fabio, Moresi, Viviana, Annibali, Daniela, Adamo, Sergio, Berardi, Emanuele
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807049/
https://ncbi.nlm.nih.gov/pubmed/27034684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6729268
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