NF-κB–mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia

Cachexia is a debilitating condition characterized by extreme skeletal muscle wasting that contributes significantly to morbidity and mortality. Efforts to elucidate the underlying mechanisms of muscle loss have predominantly focused on events intrinsic to the myofiber. In contrast, less regard has...

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Bibliographische Detailangaben
Hauptverfasser: He, Wei A., Berardi, Emanuele, Cardillo, Veronica M., Acharyya, Swarnali, Aulino, Paola, Thomas-Ahner, Jennifer, Wang, Jingxin, Bloomston, Mark, Muscarella, Peter, Nau, Peter, Shah, Nilay, Butchbach, Matthew E.R., Ladner, Katherine, Adamo, Sergio, Rudnicki, Michael A., Keller, Charles, Coletti, Dario, Montanaro, Federica, Guttridge, Denis C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809785/
https://ncbi.nlm.nih.gov/pubmed/24084740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68523
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