Oxymatrine Inhibits Renal Tubular EMT Induced by High Glucose via Upregulation of SnoN and Inhibition of TGF-β1/Smad Signaling Pathway

Transforming growth factor-β1 (TGF-β1) signaling has been shown to play a critical role in the development of diabetic nephropathy (DN). The nuclear transcription co-repressor Ski-related novel protein N (SnoN) is an important negative regulator of TGF-β1/Smad signal transduction, and subsequent bio...

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Vydáno v:PLoS One
Hlavní autoři: Liu, Lirong, Wang, Yuanyuan, Yan, Rui, Li, Shuang, Shi, Mingjun, Xiao, Ying, Guo, Bing
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807015/
https://ncbi.nlm.nih.gov/pubmed/27010330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151986
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