UmuDAb: An Error-Prone Polymerase Accessory Homolog Whose N-Terminal Domain Is Required for Repression of DNA Damage Inducible Gene Expression in Acinetobacter baylyi

In many bacteria, the DNA damage response induces genes (SOS genes) that were repressed by LexA. LexA represses transcription by binding to SOS promoters via a helix-turn-helix motif in its N-terminal domain (NTD). Upon DNA damage, LexA cleaves itself and allows induction of transcription. In Acinet...

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Veröffentlicht in:PLoS One
Hauptverfasser: Witkowski, Travis A., Grice, Alison N., Stinnett, DeAnna B., Wells, Whitney K., Peterson, Megan A., Hare, Janelle M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807011/
https://ncbi.nlm.nih.gov/pubmed/27010837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152013
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