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UmuDAb: An Error-Prone Polymerase Accessory Homolog Whose N-Terminal Domain Is Required for Repression of DNA Damage Inducible Gene Expression in Acinetobacter baylyi

In many bacteria, the DNA damage response induces genes (SOS genes) that were repressed by LexA. LexA represses transcription by binding to SOS promoters via a helix-turn-helix motif in its N-terminal domain (NTD). Upon DNA damage, LexA cleaves itself and allows induction of transcription. In Acinet...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Witkowski, Travis A., Grice, Alison N., Stinnett, DeAnna B., Wells, Whitney K., Peterson, Megan A., Hare, Janelle M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807011/
https://ncbi.nlm.nih.gov/pubmed/27010837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152013
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